Key Largo to Key West Florida Mile By Mile Guide
Key Takeaways

Last Updated June 27, 2026
We travel quite frequently and Florida road trips are our favorite. From the far reaches of the Florida Panhandle to the Southernmost Point in the Keys, we love it all.
Yet, there are few road trips we look forward to more than our almost-annual road trip from Key Largo to Key West. The beauty, the quirky sights, the craziness on Duval Street, and the serenity of beaches along the way – it is always a fascinating, new and exciting trip.
We are tracing our steps over the years into a Key Largo to Key West Florida Mile by Mile Guide. We take you along on things to do in the Florida Keys, places to stay in the Keys and the fun things to do in the 100-plus miles of the Overseas Highway.
How Far is the Drive from Key Largo to Key West
Technically, Key Largo starts at MM (mile marker) 107 and ends at MM 0 in Key West. The trip seems to start earlier when you enter the long highway to Key Largo at MM 126.
All of a sudden, you are on a small strip of land with a four-lane highway surrounded by water and mangroves by MM 107.
The initial journey has a Florida Keys feel as you leave the mainland in Homestead, Florida.

We should explain that our Key Largo to Key West Florida Mile by Mile Guide uses Mile Markers to denote our location as we travel through the Keys. Each mile is marked by a green and white mile marker sign along the side of the road.
For instance, you will find the Jewfish Creek Drawbridge at MM 107.2 as you enter Key Largo. That means it is 2/10s of a mile past MM 107. You are traveling on the famous Overseas Highway, otherwise known as the last section of US Route 1, which travels over 2000 miles up the coast of the United States all the way to Maine and southwest to Key West.
If you want a complete list of 133 Mile Markers in the Florida Keys, the post is here.
Key Largo, Florida Guide to Mile Marker 0
At MM 106, you will see the Key Largo Chamber of Commerce, but we would rather point out a more interesting stop at MM104.1, the Caribbean Club. If you are thirsty, you might make a stop here. Their claim to fame is the 1948 old movie Key Largo, which was partially filmed here. Humphrey Bogart may have shared a bar stool with you here.
Down the road at MM 104 is a better stop if you like tiki bars. Jimmy Johnson’s Big Chill, owned by the former Dallas coach, serves some rather good food and has a huge tiki bar built over the water on the bayside.
If you are looking for a place to stay before you complete your journey to Key West, the Reefhouse Resort & Marina at MM103.8 is excellent. The Reefhouse sunset bar, Breezer’s, is a fabulous place for appetizers and watching the sun creep into the bay. The photo at the left was taken from the landing at Breezer’s.
A mile down the road is the entrance to John Pennekamp State Park. There are a plethora of state parks in Florida and several along your way to Key West. What makes this one different is that 75 square miles of it is underwater!
There are hiking trails and things to see on shore, but this park is made for snorkelers and divers. It’s worth the stop just to see the park’s information center with information about the reefs, diving and snorkeling in the Keys.
By the time you get to MM 100, you may be getting hungry. If so, look for Skippers Dockside on the oceanside. It is a little off the main road, but the food is better than average. Try the shrimp ceviche for a good Florida appetizer.
If lunch is on your mind, we have an excellent suggestion. Key Largo Fisheries is three or four blocks off the Overseas Highway at 1313 Ocean Bay Drive on the oceanside. You can expect the best grouper sandwich in the Florida Keys here.
Everything You Need to Know About Key Largo in FAQs
Best Things To Do in Key Largo
Best Places To Stay in Key Largo
Tavernier Florida
Back on the road as you enter the next town, Tavernier, Florida, at about MM 93.6 is the Florida Keys Wild Bird Center. These people do great work rescuing birds that have been injured or entangled by fishing lines or nets. You can see numerous species in their rehab center. A kind donation would help preserve the Keys’ wildlife.
We must insert a note about things to see and do. The drive along US 1 in the Keys has all kinds of attractions, sights, unique shops, and places you may want to see. The ones listed here are just a few recommendations along the way. It’s over 100 miles of scenery, waterfront views and sights along the road!
If we listed every interesting site and attraction, you would not get to Key West until the following week. Our select items to see and do are included.
Islamorada Florida

At MM 84.2, you will see a big sign advertising the Theater of the Sea. Try to plan a visit. The Theater is just that – a tropical stage to interact with dolphins, sea lions, sea turtles, fish, sharks, stingrays, alligators, and birds.
The surroundings are a lush tropical setting for learning about Florida’s aquatic wildlife. This attraction is a great place for kids and adults to learn about the magnificent creatures of the sea.
After leaving the Theater of the Sea, just ¼ mile down the road is the Three Waters Resort & Marina (formerly the Post Card Inn). The reason Three Waters is significant is the huge fleet of fishing charter boats anchored at their very new (2025) marina and the spectacular views from their oceanfront accommodations.
Best Things To Do in Islamorada Florida
Overseas Highway and The Bridges in the Keys

There are about 1700 islands in the Keys and only 42 bridges. Obviously, most islands are not connected by bridges but are a vital part of the estuary of the Keys.
One very special bridge is heading over to Matecumbe Key, at MM 77. Just at the base of the far west end of the bridge, you will see a big sign that says ROBBIE’S. Robbie’s has become a major attraction for travelers in the Keys.
Thousands of people stop to hand feed tarpon that weighs more than most teenagers! Robbie’s also has a collection of little tent stores that sell everything from baubles to beads and everything from “Florida” but mostly made in China!
This is an obligatory stop for the traveling first-time tourist (at least once) to feed the tarpon – if you have kids from 5 to 105, they will love it!

On down the road about ten miles, at MM 67.5, is the Long Key State Park. What a great place to hike, swim, camp or just stroll around the park. This is one of Florida’s many state parks that is unique because of the Atlantic Ocean view and the rustic grounds!

Before you get tired of walking the ocean side, save some energy for one of the most famous family-oriented fishing resorts in the world – Hawks Cay Resort is at MM 61.1.
If you have ever watched any outdoor shows, Hawks Cay has been featured many times showing the bounty of nearby waters. This is a place for good old-fashioned family fun.
The resort has every possible saltwater activity, with the focus on sport fishing. The kids will have fun too with a huge pool, paddle boards and daily planned activities. The food is exceptional, so lunch on the way down the Keys is a great stop at their Angler & Ale restaurant.
In our opinion, Hawks Cay is the best family resort in the Florida Keys. Find out about rates here.
If you have kids, 5 to 95, The Dolphin Research Center is at MM 58.9. This place is for family fun and they do great work to preserve our dolphin population. They have a research center and a large contained area in Florida Bay where they rehab and train dolphins. The kids love it (and adults too).
By the time you get to MM 53.5, you will be in Marathon, Florida. A city of about 8500 people stretching over several keys (islands), Marathon is considered halfway to Key West and you will see the obligatory businesses that are named “Halfway Bakery”, “Halfway Cleaners, etc.”.
One large development in Marathon is Key Colony Beach – a community with over 400 homes on a large peninsula out in the Atlantic Ocean. Few communities exist in the Keys of this size. A quick drive-through might be an interesting glimpse of how people live in this part of paradise!
Perhaps the most interesting place of all the attractions we discuss is at MM 50. Crane Point Museum and Nature Center is one of the coolest places to find out about the Florida Key’s history, nature, and early life in the islands – all in one
place! This is a privately operated attraction that offers exceptional opportunities to see and feel how it must have been to survive on this strip of land a couple hundred years ago.
Of the nature trails on these 63 acres is one that leads to the Adderley House, a home built about 1903 from materials found around Vaca Key. It survives today to remind us of the hardships faced by our forefathers. Make time for a couple of hours here – it’s worth the visit!
Marathon – Half Way To Mile Marker 0
We are about halfway to Key West as we enter Marathon at MM 59.9 and some of the best traveling is yet to come! In fact, you will see in the next three miles places like the Stuffed Pig, a great little locals’ place for breakfast and lunch, and then you will start seeing signs like the 7 Mile Pizzeria and the 7 Mile Bar & Grill – heads up!
You are coming to the most spectacular views on your entire trip – The Seven Mile Bridge!
The current Seven Mile Bridge was completed in 1982 and was one of the largest bridges in the world at that time. Alongside the new bridge, you will see the remnants of a railroad bridge Henry Flagler completed to Key West in 1912.
Flagler’s Bridge brought tourists and products to and from Key West leading to twenty-plus years of prosperity until the Great Labor Day Hurricane of 1935 destroyed the bridge structure. In the face of this destruction, the United States bought the right of way from the railroad and made a bridge for automobile traffic from the remaining structure.
The back story and history of the bridge are fascinating, but the real story is in the spectacular views on both sides of the bridge. Florida Bay on your right and the Atlantic Ocean on your left make keeping your eyes on the road nearly impossible.
You will see ships on the horizon in the Atlantic and bay fishermen looking for snook and tarpon in the shallows. The sparkling blueish-green water laps the pylons of the bridge along with the waves produced by the boat traffic underneath.
Sunrises and sunsets are breathtaking! Seven miles is a long way to travel on a bridge, but the time seems but a small few minutes you hate to see the end.
After about 7 miles (imagine that, on the seven-mile bridge), the bridge comes to an end! By now you are awestruck with the beauty of the Florida Keys. But as hard as it is to imagine, at MM 36.8, get ready for a whole new close-up experience at Bahia Honda State Park.
This park has all the normal things state parks have, hiking, camping, swimming and more. But Bahia Honda offers a unique chance to get in the water and snorkel over the shallows to see another whole world beneath the surface of the Ocean.
This park is a family favorite due to the relatively shallow water and the ability to give children more than a cursory education about marine life. Relax and look around, your next adventure may just be underwater! Our family tells stories about their first encounters with the creatures of the sea, and their memories as they became acquainted with the saltwater environment at Bahia Honda.
Things To Do in Marathon Florida Keys
Big Pine Key and Key Deer

We must move on since you can almost taste the margaritas in Key West in an hour or so away. Across the bridge going south you will start seeing warnings about one of the strangest animals in the Keys – the Key Deer.
These dog size animals can be seen day or night on Big Pine Key. They look exactly like their full-sized white-tailed cousins in the woods of the Midwest, but are just about one-third the size. The Key Deer is an endangered species and lives only in this area. Their biggest enemy is man and the cars they drive. That is why speed limits are reduced and so you can keep a watchful eye out for the deer on the island.

While you are on Big Pine Key, and if you aren’t late for happy hour in Key West, you may want to set your GPS for another part of the island where the No Name Pub resides. This is a dive bar that has become an institution by selling the idea they are an old bar littered with thousands of dollar bills covering every imaginable inch of its walls.
I admit it is a sight to see, but the sight is short-lived once you get on down the road to Key West with dozens of quirky bars!
If you need to make a stop somewhere you may want to try Boondocks around MM 27 or Mangrove Mamas down the road, but you are now just about 20 minutes from Stock Island, which we consider part of Key West.
There are a few bars, a naval air station and a couple sights along the way, but few people can bring themselves to stop when they know the excitement of Key West lies just minutes ahead.
Mile-by-Mile Key Largo to Key West Ends – But The Fun in Key West is Just Beginning
We have been to Key West at least 30 times. We haven’t always driven, but time allowing, we prefer the drive. We try to cross those 42 bridges at least a couple times annually. No matter how many times I look out that windshield at that final little bridge over a canal that separates Key West from Stock Island, my level of anticipation peaks at a new level.
We always wonder, what has changed? Something always changes. Is there a cruise ship in town? Not as many as there were when cruise ships were allowed to go to Cuba. Any new bars? There are always new bars! Are any old favorites closed? There are always a few that close!
Change seems to only affect the fringes in the Conch Republic, the local’s name for Key West. Key West got the name Conch Republic when Key Westers got tired of Custom’s officers blocking traffic to the island. The government claimed
they were looking for illegal aliens (better known as immigrants), but Key West residents swore it was drugs they were looking for. So all in one day in 1982, the mayor and a few of his cohorts decided the city should secede from the United States! They declared a secession, called the new country the Conch Republic, marched to the naval base, declared war, surrendered immediately to the naval commander in charge, and subsequently demanded one million dollars in reparations.
We don’t think they got the money, but they did get the attention of the international media which caused enough pressure on officials to stop the roadblocks. That’s how the Conch Republic got its name!
The Attractions of Key West
The first thing you need to know is there are about 190 bars on this two-mile by four-mile island – that’s about four times the number of churches – and that’s Key West! Picking the best bars becomes an occupation for some residents of Key West and an obsession for visitors. You can break “best” down into categories – ones you have visited and ones you haven’t! We are not convinced there is a BAD bar on the island – just different.
Then there are the great restaurants of Key West that serve some of the freshest seafood in the world. We highlight the best.
Finally, we give you a list of the attractions, things to see, and things to do in Key West. Some you can consider a must-do for first-timers and others can help to bring you back again. We start with the bars of Key West.
Tourists Must See Iconic Key West Bars and Attractions

There are bars in Key West that have a worldwide reputation and your friends, neighbors and relatives might think you were strange if you didn’t visit the basic watering holes! The List includes:
- Sloppy Joe’s – The iconic bar Hemingway frequented on his many trips to Key West.
- Captain Tony’s – The bar that was Sloppy Joe’s until they moved it in the middle of the night!
- Irish Kevin’s – Irreverence and raunchy songs mid-morning to the wee hours. Not for kids!
- Hog’s Breath Saloon – Good entertainment and better than average bar food.
- The Green Parrot – One of the oldest bars in Key West known for bands at night and dogs in the day!
- Half Shell Raw Bar – Great place to get fresh oysters and brew on the waterfront.
- Schooner Wharf – A locals favorite in the marina.
- Jimmy Buffet’s Margaritaville – The late singer’s first store.
- La Te Da – The palace of drag queens.
This is just a few of the many well-known hangouts in Key West. Some lesser-known places we like include Shots and Giggles behind Sloppy Joe’s, The Chart Room in the Pier House Hotel, and The Bull at Caroline Street and Duval Street.
The Top Ten Things You Must Do in Key West
- Mallory Square at Sunset -The quintessential thing to do in Key West. See the sunset and performers each evening.
- Hemingway House – The home of the most famous writer in Key West.
- Southernmost Buoy – The must-have picture of you and the famous location.
- Museum of Art and History – A great rainy day activity. The Museum is excellent.
- The Key West Aquarium – Get an understanding of the creatures of the sea.
- Mel Fisher Maritime Museum – The museum of the man who found a fortune at the bottom of the sea.
- Butterfly and Nature Conservatory – Beautiful scenery and butterflies.
- Fort Zachary Taylor – Visit the Fort and one of the best beaches in Key West.
- Key West Lighthouse – See the keeper’s quarters and walk the stairs to the highest point in Key West.
- Dry Tortugas – Fort Jefferson – Our favorite thing to do in Key West. Take a trip over to the Dry Tortugas and visit the Fort. Great snorkeling too!
The Watersports of Key West Things To Do
With water total surrounding the island, there are many opportunities to engage in watersports that you may not be able to do anywhere else in the country. Our suggestions for water sport things to do in Key West include:
- Charter a fishing trip. Some of the best inshore and offshore fishing in the country is right here in Key West.
A sailing trip in Key West is always a lot of group fun. - Learn how to scuba dive or snorkel in the crystal clear waters around Key West.
- Charter a sunset sailing cruise for a memorable evening.
- Jet skis, paddle boards and kayaks are all available for rent. We had a memorable time on a jet ski-guided tour of the island.
Best Places To Stay in Key West
There are well over 150 hotels in Key West and another 50 or more bed and breakfast lodgings. Choices range from big chain hotels to local independent owners. Prices are as varied as amenities.
Bed and Breakfast Recommendation
The Conch House Heritage Inn. The Conch House is in Old Town and is roomy and clean according to friends who have stayed there. Of course, breakfast is offered in the mornings there as well.
Hotels in Key West We Can Recommend
There are an abundance of hotels on every part of the island. Every chain has a location somewhere in Key West. You can spend time looking on the travel sites or below are the ones we have stayed in that we recommend. (There are others we have stayed in we won’t be mentioning.)

The Pier House – We have stayed here many times. Right at the foot of Duval Street. The Chart Room, one of our favorite Bars, is located inside. They are on the high end from a cost standpoint. The location, clean rooms and waterside bar make it worthwhile. They also have a small private beach and a nice pool.
All the way to the other end of Duval Street (south) is the Casa Marina, part of the Hilton Curio group of hotels. This gracefully aging beauty was opened in 1920 as part of the Henry Flagler group of exclusive hotels he was building along the coast. This hotel is immaculate, exclusive, and right on the Atlantic Ocean with their own private beach. We would highly recommend this facility, but the cost may not be worth it if you plan to spend your days off the property.
The Galleon Resort and Marina is a perfect location if you are planning on taking advantage of the many water sports in Key West. The hotel is on the Gulf side of the Island and has a 90-slip boat marina. They also are a time-share resort, so availability may be limited at certain times of the year. They are priced about the same as the Pier House year-round.

Opal Key Resort & Marina says on their website they were ranked as one of the top resorts in the Florida Keys! We are not sure about this lofty ranking, but Margaritaville has a great location right on the entrance to the Key West Harbor. The hotel is also next to Mallory Square, with their own shops on property near their marina. This is a good hotel and will be priced as the Pier House and others.
Right in the middle of Duval Street is the Crown Plaza La Concha Hotel. We haven’t stayed here in several years, but the hotel has been remodeled recently and should be better than our last visit. The La Concha is one of the tallest buildings in Key West and has a great view of the landscape. The hotel has a large wine bar on Duval and very comfortable lobby. Pricing is just slightly less than waterfront properties.
Final Thoughts on the Key Largo to Key West Florida Mile by Mile Guide
There are many ways of getting to Key West and the Florida Keys and everyone experiences the Keys a little differently. Some are attracted to the unrivaled rich history. Others just scratch the surface for a quick get-away, much like taking Key West as nature’s Valium! Many people come for the water sports that abound in the clear blue waters. Some people love the almost 24-hour-a-day entertainment.
Annual events like the Hemingway lookalike contest, Fantasy Fest, Song Writer’s Festival, multiple fishing tournaments, food and wine festivals, Super Boat Championships, and many more bring thousands of visitors. The natural setting of islands between two oceans offers experiences not found anywhere else in the world.
For whatever reason you visit the Keys, you will always create memories that are hard to duplicate. Our Key Largo to Key West Guide hopefully added to your memorable trip through the Keys. Should you start planning a trip to the Florida Keys, use this guide as a starting point for your itinerary.
FAQs About the Key Largo Guide to Key West Mile by Mile
How far is Key Largo from Key West?
Key Largo to Key West is about 100–110 miles depending on where you start in Key Largo and where you end in Key West. Even though the distance isn’t huge, the drive can take longer than people expect because US-1 is mostly two lanes with speed changes and traffic.
How long does it take to drive from Key Largo to Key West?
Most people should plan 2.5 to 3.5 hours without long stops. On weekends, holidays, or during heavy travel periods, it can take 4+ hours with traffic and backups.
Is the drive from Key Largo to Key West scenic?
Yes—this is one of Florida’s most scenic drives. You’ll cross long bridges, see open ocean views, and pass classic Keys towns. The most famous stretch is the Seven Mile Bridge.
Is there only one road from Key Largo to Key West?
Pretty much, yes. The main route is US-1 (Overseas Highway), now called Jimmy Buffett Memorial Highway. There aren’t many true alternate roads, so accidents or construction can cause delays.
Do you drive over Seven Mile Bridge from Key Largo to Key West?
Yes. Seven Mile Bridge is on US-1 in the Middle Keys near Marathon. It’s a highlight of the drive and one of the most photographed parts of the Overseas Highway.
What are the best stops between Key Largo and Key West?
Popular stops include Islamorada (food + views), Marathon (Seven Mile Bridge area), Bahia Honda State Park (best beach-style stop), and Big Pine Key (wildlife and Key deer area).
How many bridges are on the way from Key Largo to Key West?
The Overseas Highway includes dozens of bridges between the Keys. People often cite 42 bridges for the full Overseas Highway drive to Key West, and you’ll cross many of them on the Key Largo to Key West route.
What is the best time to drive from Key Largo to Key West?
Leave early in the morning for the smoothest drive and calmer water views. Midday on weekends can be slow, and late afternoon can also back up near popular towns and bridge bottlenecks.
Is the drive from Key Largo to Key West safe?
Yes, but it’s a slower, more attentive drive than many people expect. Watch speed changes, passing zones, cyclists, and bridges. Drive patiently—locals and visitors share the same two-lane highway.
Are there tolls driving from Key Largo to Key West?
No. Once you’re in the Keys on US-1, there are no tolls on the Key Largo to Key West drive.
Can you do Key Largo to Key West as a day trip?
You can, but it’s a long day. With 5–7+ hours round trip plus time in Key West, many people prefer staying at least one night so it doesn’t feel rushed.
Do I need a car once I get to Key West?
Not necessarily. Key West is walkable and easy by bike or scooter, and parking can be expensive and limited. Many visitors park once and explore without driving.
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